A role for proteinase-activated receptor–1 in inflammatory bowel diseases

Proteinase-activated receptor–1 (PAR(1)), a G protein–coupled receptor activated by thrombin, is highly expressed in different cell types of the gastrointestinal tract. The activity of thrombin and of other proteinases is significantly increased in the colon of inflammatory bowel disease (IBD) patie...

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Bibliografiset tiedot
Päätekijät: Vergnolle, Nathalie, Cellars, Laurie, Mencarelli, Andrea, Rizzo, Giovanni, Swaminathan, Sunita, Beck, Paul, Steinhoff, Martin, Andrade-Gordon, Patricia, Bunnett, Nigel W., Hollenberg, Morley D., Wallace, John L., Cirino, Giuseppe, Fiorucci, Stefano
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2004
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC526028/
https://ncbi.nlm.nih.gov/pubmed/15545995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421689
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