A role for proteinase-activated receptor–1 in inflammatory bowel diseases

Proteinase-activated receptor–1 (PAR(1)), a G protein–coupled receptor activated by thrombin, is highly expressed in different cell types of the gastrointestinal tract. The activity of thrombin and of other proteinases is significantly increased in the colon of inflammatory bowel disease (IBD) patie...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Vergnolle, Nathalie, Cellars, Laurie, Mencarelli, Andrea, Rizzo, Giovanni, Swaminathan, Sunita, Beck, Paul, Steinhoff, Martin, Andrade-Gordon, Patricia, Bunnett, Nigel W., Hollenberg, Morley D., Wallace, John L., Cirino, Giuseppe, Fiorucci, Stefano
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2004
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC526028/
https://ncbi.nlm.nih.gov/pubmed/15545995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421689
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