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3D clusters of somatic mutations in cancer reveal numerous rare mutations as functional targets
Many mutations in cancer are of unknown functional significance. Standard methods use statistically significant recurrence of mutations in tumor samples as an indicator of functional impact. We extend such analyses into the long tail of rare mutations by considering recurrence of mutations in cluste...
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| 出版年: | Genome Med |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5260099/ https://ncbi.nlm.nih.gov/pubmed/28115009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-016-0393-x |
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