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Decoding the role of the nuclear receptor SHP in regulating hepatic stellate cells and liver fibrogenesis

The small heterodimer partner (SHP) is an orphan nuclear receptor that lacks the DNA binding domain while conserves a putative ligand-binding site, thought that endogenous ligands for this receptor are unknown. Previous studies have determined that SHP activation protects against development of live...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Cipriani, Sabrina, Carino, Adriana, Masullo, Dario, Zampella, Angela, Distrutti, Eleonora, Fiorucci, Stefano
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5259793/
https://ncbi.nlm.nih.gov/pubmed/28117422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41055
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