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Decoding the role of the nuclear receptor SHP in regulating hepatic stellate cells and liver fibrogenesis

The small heterodimer partner (SHP) is an orphan nuclear receptor that lacks the DNA binding domain while conserves a putative ligand-binding site, thought that endogenous ligands for this receptor are unknown. Previous studies have determined that SHP activation protects against development of live...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Cipriani, Sabrina, Carino, Adriana, Masullo, Dario, Zampella, Angela, Distrutti, Eleonora, Fiorucci, Stefano
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5259793/
https://ncbi.nlm.nih.gov/pubmed/28117422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41055
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