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Decoding the role of the nuclear receptor SHP in regulating hepatic stellate cells and liver fibrogenesis

The small heterodimer partner (SHP) is an orphan nuclear receptor that lacks the DNA binding domain while conserves a putative ligand-binding site, thought that endogenous ligands for this receptor are unknown. Previous studies have determined that SHP activation protects against development of live...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cipriani, Sabrina, Carino, Adriana, Masullo, Dario, Zampella, Angela, Distrutti, Eleonora, Fiorucci, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5259793/
https://ncbi.nlm.nih.gov/pubmed/28117422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41055
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