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Production of functional human nerve growth factor from the saliva of transgenic mice by using salivary glands as bioreactors

The salivary glands of animals have great potential to act as powerful bioreactors to produce human therapeutic proteins. Human nerve growth factor (hNGF) is an important pharmaceutical protein that is clinically effective in the treatment of many human neuronal and non-neuronal diseases. In this st...

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書誌詳細
出版年:Sci Rep
主要な著者: Zeng, Fang, Li, Zicong, Zhu, Qingchun, Dong, Rui, Zhao, Chengcheng, Li, Guoling, Li, Guo, Gao, Wenchao, Jiang, Gelong, Zheng, Enqin, Cai, Gengyuan, Moisyadi, Stefan, Urschitz, Johann, Yang, Huaqiang, Liu, Dewu, Wu, Zhenfang
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5259756/
https://ncbi.nlm.nih.gov/pubmed/28117418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41270
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