CRISPR/Cas9-Mediated Integration of Large Transgene into Pig CEP112 Locus

Clustered regularly interspaced short palindromic repeats (CRISPR)-associated protein 9 (Cas9) is a precise genome manipulating tool that can produce targeted gene mutations in various cells and organisms. Although CRISPR/Cas9 can efficiently generate gene knockout, the gene knock-in (KI) efficiency...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Li, Guoling, Zhang, Xianwei, Wang, Haoqiang, Mo, Jianxin, Zhong, Cuili, Shi, Junsong, Zhou, Rong, Li, Zicong, Yang, Huaqiang, Wu, Zhenfang, Liu, Dewu
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2019
Assuntos:
Genome Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7003105/
https://ncbi.nlm.nih.gov/pubmed/31818875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.119.400810
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