Engineering the substrate specificity of glutathione reductase toward that of trypanothione reduction.

Glutathione reductase (EC 1.6.4.2; CAS registry number 9001-48-3) and trypanothione reductase (CAS registry number 102210-35-5), which are related flavoprotein disulfide oxidoreductases, have marked specificities for glutathione and trypanothione, respectively. A combination of primary sequence alig...

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Hauptverfasser: Henderson, G B, Murgolo, N J, Kuriyan, J, Osapay, K, Kominos, D, Berry, A, Scrutton, N S, Hinchliffe, N W, Perham, R N, Cerami, A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1991
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC52591/
https://ncbi.nlm.nih.gov/pubmed/1924337
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