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X-ray structure of trypanothione reductase from Crithidia fasciculata at 2.4-A resolution.

Trypanosomes and related protozoan parasites lack glutathione reductase and possess instead a closely related enzyme that serves as the reductant of a bis(glutathione)-spermidine conjugate, trypanothione. The human and parasite enzymes have mutually exclusive substrate specificities, providing a rou...

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Autors principals: Kuriyan, J, Kong, X P, Krishna, T S, Sweet, R M, Murgolo, N J, Field, H, Cerami, A, Henderson, G B
Format: Artigo
Idioma:Inglês
Publicat: 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC52590/
https://ncbi.nlm.nih.gov/pubmed/1924336
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