PARP-1 Controls the Adipogenic Transcriptional Program by PARylating C/EBPβ and Modulating Its Transcriptional Activity

Poly(ADP-ribosyl)ation (PARylation) is a post-translational modification of proteins mediated by PARP family members, such as PARP-1. Although PARylation has been studied extensively, few examples of definitive biological roles for site-specific PARylation have been reported. Here we show that C/EBP...

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Publicat a:Mol Cell
Autors principals: Luo, Xin, Ryu, Keun Woo, Kim, Dae-Seok, Nandu, Tulip, Medina, Carlos J., Gupte, Rebecca, Gibson, Bryan A., Soccio, Raymond E., Yu, Yonghao, Gupta, Rana K., Kraus, W. Lee
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5258183/
https://ncbi.nlm.nih.gov/pubmed/28107648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.11.015
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