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Metabolic Regulation of Transcription Through Compartmentalized NAD(+) Biosynthesis
NAD(+) is an essential molecule for a variety of physiological processes. It is synthesized in distinct subcellular compartments by three different NAD(+) synthases (NMNATs 1, 2, and 3). We found that compartmentalized NAD(+) synthesis by NMNATs integrates glucose metabolism and adipogenic transcrip...
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| Publicado no: | Science |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6465534/ https://ncbi.nlm.nih.gov/pubmed/29748257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aan5780 |
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