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Solid-State NMR Investigation of the Conformation, Proton Conduction, and Hydration of the Influenza B Virus M2 Transmembrane Proton Channel

Together with the influenza A virus, influenza B virus causes seasonal flu epidemics. The M2 protein of influenza B (BM2) forms a tetrameric proton-conducting channel that is important for the virus lifecycle. BM2 shares little sequence homology with AM2, except for a conserved HxxxW motif in the tr...

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Publicat a:J Am Chem Soc
Autors principals: Williams, Jonathan K., Tietze, Daniel, Lee, Myungwoon, Wang, Jun, Hong, Mei
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5257200/
https://ncbi.nlm.nih.gov/pubmed/27286559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b03142
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