Triple negative breast cancers with amplification of JAK2 at the 9p24 loci demonstrate JAK2-specific dependence

Amplifications at 9p24 have been identified in breast cancer and other malignancies, but the genes within this locus casually associated with oncogenicity or tumor progression remain unclear. Targeted next-generation sequencing of post-chemotherapy triple-negative breast cancers (TNBC) identified a...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Balko, Justin M., Schwarz, Luis J., Cook, Rebecca S., Estrada, Monica V., Giltnane, Jennifer M., Sanders, Melinda E., Sánchez, Violeta, Dean, Phillip T., Wang, Kai, Combs, Susan E., Hicks, Donna, Pinto, Joseph A., Landis, Melissa D., Chang, Jenny C., Doimi, Franco D., Gómez, Henry, Rimm, David L., Yelensky, Roman, Miller, Vincent A., Stephens, Phillip J., Arteaga, Carlos L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5256931/
https://ncbi.nlm.nih.gov/pubmed/27075627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aad3001
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