Leukemia cell proliferation and death in chronic lymphocytic leukemia patients on therapy with the BTK inhibitor ibrutinib

BACKGROUND. Ibrutinib is an effective targeted therapy for patients with chronic lymphocytic leukemia (CLL) that inhibits Bruton’s tyrosine kinase (BTK), a kinase involved in B cell receptor signaling. METHODS. We used stable isotopic labeling with deuterated water ((2)H(2)O) to measure directly the...

詳細記述

保存先:
書誌詳細
出版年:JCI Insight
主要な著者: Burger, Jan A., Li, Kelvin W., Keating, Michael J., Sivina, Mariela, Amer, Ahmed M., Garg, Naveen, Ferrajoli, Alessandra, Huang, Xuelin, Kantarjian, Hagop, Wierda, William G., O’Brien, Susan, Hellerstein, Marc K., Turner, Scott M., Emson, Claire L., Chen, Shih-Shih, Yan, Xiao-Jie, Wodarz, Dominik, Chiorazzi, Nicholas
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2017
主題:
Clinical Medicine
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5256142/
https://ncbi.nlm.nih.gov/pubmed/28138560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89904
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料