Randomized trial of ibrutinib vs ibrutinib plus rituximab in patients with chronic lymphocytic leukemia

Ibrutinib, an oral covalent inhibitor of Bruton’s tyrosine kinase, is an effective therapy for patients with chronic lymphocytic leukemia (CLL). To determine whether rituximab provides added benefit to ibrutinib, we conducted a randomized single-center trial of ibrutinib vs ibrutinib plus rituximab....

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Detalles Bibliográficos
Publicado en:Blood
Main Authors: Burger, Jan A., Sivina, Mariela, Jain, Nitin, Kim, Ekaterina, Kadia, Tapan, Estrov, Zeev, Nogueras-Gonzalez, Graciela M., Huang, Xuelin, Jorgensen, Jeffrey, Li, Jianling, Cheng, Mei, Clow, Fong, Ohanian, Maro, Andreeff, Michael, Mathew, Thomas, Thompson, Philip, Kantarjian, Hagop, O’Brien, Susan, Wierda, William G., Ferrajoli, Alessandra, Keating, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2019
Assuntos:
Plenary Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405333/
https://ncbi.nlm.nih.gov/pubmed/30530801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-10-879429
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