Dissection of the enhancer activity of beta-globin 5' DNase I-hypersensitive site 2 in transgenic mice.

The beta-globin locus control region (LCR) consists of four erythroid-specific DNase I-hypersensitive sites, which are necessary for high-level expression of the beta-like globin genes in erythroid tissues. One of these sites, designated 5'HS-2, functions as an erythroid-specific enhancer eleme...

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Bibliographic Details
Main Authors: Liu, D, Chang, J C, Moi, P, Liu, W, Kan, Y W, Curtin, P T
Format: Artigo
Language:Inglês
Published: 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC525598/
https://ncbi.nlm.nih.gov/pubmed/1570310
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