Nalaganje...

Inactivation of the Mgat1 Gene in Oocytes Impairs Oogenesis, but Embryos Lacking Complex and Hybrid N-Glycans Develop and Implant

Complex and hybrid N-glycans contain sugar residues that have been implicated in fertilization, compaction of the embryo, and implantation. Inactivation of the Mgat1 gene responsible for their synthesis is embryonic lethal, but homozygous mutant blastocysts are phenotypically normal due to the prese...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Shi, Shaolin, Williams, Suzannah A., Seppo, Antti, Kurniawan, Henry, Chen, Wei, Ye, Zhengyi, Marth, Jamey D., Stanley, Pamela
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC525483/
https://ncbi.nlm.nih.gov/pubmed/15509794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.22.9920-9929.2004
Oznake: Označite
Brez oznak, prvi označite!