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Point mutations that inactivate MGAT4D-L, an inhibitor of MGAT1 and complex N-glycan synthesis
The membrane-bound, long form of MGAT4D, termed MGAT4D-L, inhibits MGAT1 activity in transfected cells and reduces the generation of complex N-glycans. MGAT1 is the GlcNAc-transferase that initiates complex and hybrid N-glycan synthesis. We show here that Drosophila MGAT1 was also inhibited by MGAT4...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7549026/ https://ncbi.nlm.nih.gov/pubmed/32763972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014784 |
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