Inactivation of the Mgat1 Gene in Oocytes Impairs Oogenesis, but Embryos Lacking Complex and Hybrid N-Glycans Develop and Implant

Complex and hybrid N-glycans contain sugar residues that have been implicated in fertilization, compaction of the embryo, and implantation. Inactivation of the Mgat1 gene responsible for their synthesis is embryonic lethal, but homozygous mutant blastocysts are phenotypically normal due to the prese...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Shi, Shaolin, Williams, Suzannah A., Seppo, Antti, Kurniawan, Henry, Chen, Wei, Ye, Zhengyi, Marth, Jamey D., Stanley, Pamela
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2004
Gaiak:
Cell Growth and Development
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC525483/
https://ncbi.nlm.nih.gov/pubmed/15509794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.22.9920-9929.2004
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