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Premature Ovarian Failure in Mice with Oocytes Lacking Core 1-Derived O-Glycans and Complex N-Glycans

Premature ovarian failure (POF) affects up to 1.4% of women under the age of 40 yr and less than 30% of cases have a known cause. Here we describe a new mouse model of POF resulting from oocyte-specific ablation of core 1-derived (mucin) O-glycans and complex and hybrid N-glycans. Females carrying f...

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Detalles Bibliográficos
Main Authors: Williams, Suzannah A., Stanley, Pamela
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040049/
https://ncbi.nlm.nih.gov/pubmed/21239444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0917
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