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Putative irreversible inhibitors of the human sodium-dependent bile acid transporter (hASBT; SLC10A2) support the role of transmembrane domain 7 in substrate binding/translocation
PURPOSE: The objective of this work was to explore the involvement of transmembrane domain (TM) 7 of the human apical sodium-dependent bile acid transporter (hASBT) on bile acid (BA) binding/translocation, using two electrophilic BA derivatives as molecular probes. METHODS: Two electrophilic derivat...
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| Gepubliceerd in: | Pharm Res |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5252617/ https://ncbi.nlm.nih.gov/pubmed/22354836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-012-0706-8 |
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