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Transmembrane Domain II of the Human Bile Acid Transporter SLC10A2 Coordinates Sodium Translocation

Human apical sodium-dependent bile acid transporter (hASBT, SLC10A2) is responsible for intestinal reabsorption of bile acids and plays a key role in cholesterol homeostasis. We used a targeted and systematic approach to delineate the role of highly conserved transmembrane helix 2 on the expression...

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Detalhes bibliográficos
Main Authors: Sabit, Hairat, Mallajosyula, Sairam S., MacKerell, Alexander D., Swaan, Peter W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820874/
https://ncbi.nlm.nih.gov/pubmed/24045943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.518555
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