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Transmembrane Domain V Plays a Stabilizing Role in the Function of Human Bile Acid Transporter SLC10A2

The human apical sodium-dependent bile acid transporter (hASBT, SLC10A2), primarily expressed in the ileum, is involved in both the recycling of bile acids and cholesterol homeostasis. In this study, the structure-function relationship of transmembrane domain 5 (TM5) residues involved in transport i...

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Main Authors: Moore, Robyn H., Chothe, Paresh, Swaan, Peter W.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812428/
https://ncbi.nlm.nih.gov/pubmed/23815591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400028q
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