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DNA methyltransferases and their roles in tumorigenesis

DNA methylation plays an important role in gene expression, chromatin stability, and genetic imprinting. In mammals, DNA methylation patterns are written and regulated by DNA methyltransferases (DNMTs), including DNMT1, DNMT3A and DNMT3B. Recent emerging evidence shows that defects in DNMTs are invo...

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Detalhes bibliográficos
Publicado no:Biomark Res
Main Authors: Zhang, Wu, Xu, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5251331/
https://ncbi.nlm.nih.gov/pubmed/28127428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40364-017-0081-z
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