The Yin-Yang of DNA Damage Response: Roles in Tumorigenesis and Cellular Senescence

Senescent cells are relatively stable, lacking proliferation capacity yet retaining metabolic activity. In contrast, cancer cells are rather invasive and devastating, with uncontrolled proliferative capacity and resistance to cell death signals. Although tumorigenesis and cellular senescence are see...

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Detalhes bibliográficos
Main Authors: Li, Xiaoman, Xu, Hongde, Xu, Chongan, Lin, Meina, Song, Xiaoyu, Yi, Fei, Feng, Yanling, Coughlan, Kathleen A., Cho, William Chi-shing, Kim, Sang Soo, Cao, Liu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587995/
https://ncbi.nlm.nih.gov/pubmed/23354477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms14022431
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