The Yin-Yang of DNA Damage Response: Roles in Tumorigenesis and Cellular Senescence

Senescent cells are relatively stable, lacking proliferation capacity yet retaining metabolic activity. In contrast, cancer cells are rather invasive and devastating, with uncontrolled proliferative capacity and resistance to cell death signals. Although tumorigenesis and cellular senescence are see...

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Bibliografiske detaljer
Main Authors: Li, Xiaoman, Xu, Hongde, Xu, Chongan, Lin, Meina, Song, Xiaoyu, Yi, Fei, Feng, Yanling, Coughlan, Kathleen A., Cho, William Chi-shing, Kim, Sang Soo, Cao, Liu
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2013
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587995/
https://ncbi.nlm.nih.gov/pubmed/23354477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms14022431
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