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Telomere Length and Telomerase Activity; A Yin and Yang of Cell Senescence

Telomeres are repeating DNA sequences at the tip ends of the chromosomes that are diverse in length and in humans can reach a length of 15,000 base pairs. The telomere serves as a bioprotective mechanism of chromosome attrition at each cell division. At a certain length, telomeres become too short t...

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Bibliographic Details
Main Authors: Axelrad, Mary Derasmo, Budagov, Temuri, Atzmon, Gil
Format: Artigo
Language:Inglês
Published: MyJove Corporation 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711628/
https://ncbi.nlm.nih.gov/pubmed/23728273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/50246
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