GSK3β activity is essential for senescence-associated heterochromatin foci (SAHF) formation induced by HMGA2 in WI38 cells

Cellular senescence is an irreversible form of cell cycle arrest, which is often characterized by domains of facultative heterochromatin substructures also known as senescence-associated heterochromatin foci (SAHF). SAHF assembly is likely mediated through the downregulation of the Wnt pathway, whic...

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Veröffentlicht in:Am J Transl Res
Hauptverfasser: Shi, Xi, Tian, Baoqing, Ma, Chi, Liu, Lingxia, Zhang, Na, Na, Yuan, Li, Jing, Lu, Jun, Qiao, Yuehua
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5250713/
https://ncbi.nlm.nih.gov/pubmed/28123643
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