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HDACs and the senescent phenotype of WI-38 cells

BACKGROUND: Normal cells possess a limited proliferative life span after which they enter a state of irreversible growth arrest. This process, known as replicative senescence, is accompanied by changes in gene expression that give rise to a variety of senescence-associated phenotypes. It has been su...

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Detalhes bibliográficos
Main Authors: Place, Robert F, Noonan, Emily J, Giardina, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1285358/
https://ncbi.nlm.nih.gov/pubmed/16250917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-6-37
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