GSK3β activity is essential for senescence-associated heterochromatin foci (SAHF) formation induced by HMGA2 in WI38 cells

Cellular senescence is an irreversible form of cell cycle arrest, which is often characterized by domains of facultative heterochromatin substructures also known as senescence-associated heterochromatin foci (SAHF). SAHF assembly is likely mediated through the downregulation of the Wnt pathway, whic...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Shi, Xi, Tian, Baoqing, Ma, Chi, Liu, Lingxia, Zhang, Na, Na, Yuan, Li, Jing, Lu, Jun, Qiao, Yuehua
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5250713/
https://ncbi.nlm.nih.gov/pubmed/28123643
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