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Memory CD4(+) T cells are suppressed by CD8(+) regulatory T cells in vitro and in vivo

Background: Acute graft rejection mediated by alloreactive memory CD4(+) T cells is a major obstacle to transplantation tolerance. It has been reported that CD8(+) T regulatory cells (Tregs) have the ability to induce graft tolerance by restraining the function of activated CD4(+) T cells, but not i...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Long, Xin, Cheng, Qi, Liang, Huifang, Zhao, Jianping, Wang, Jian, Wang, Wei, Tomlinson, Stephen, Chen, Lin, Atkinson, Carl, Zhang, Bixiang, Chen, Xiaoping, Zhu, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5250704/
https://ncbi.nlm.nih.gov/pubmed/28123634
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