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CD4(+)CD25(+) regulatory T cells suppress allograft rejection mediated by memory CD8(+) T cells via a CD30-dependent mechanism

CD4(+)CD25(+) regulatory T (Treg) cells suppress naive T cell responses, prevent autoimmunity, and delay allograft rejection. It is not known, however, whether Treg cells suppress allograft rejection mediated by memory T cells, as the latter mount faster and stronger immune responses than their naiv...

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Detalhes bibliográficos
Main Authors: Dai, Zhenhua, Li, Qi, Wang, Yinong, Gao, Ge, Diggs, Lonnette S., Tellides, George, Lakkis, Fadi G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC311434/
https://ncbi.nlm.nih.gov/pubmed/14722622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200419727
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