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Neutralizing IL-6 reduces human arterial allograft rejection by allowing emergence of CD161(+) CD4(+) T regulatory cells,2,
Peri-operative injuries to an allograft exacerbate graft rejection, which, in humans, is primarily mediated by effector memory T cells. IL-6 transcripts are elevated in human coronary artery segments rapidly increase post-transplantation into immunodeficient mouse hosts compared to pre-transplant sp...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3237826/ https://ncbi.nlm.nih.gov/pubmed/22084439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003774 |
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