RNA Degradation Induced by the Herpes Simplex Virus vhs Protein Proceeds 5′ to 3′ In Vitro

The herpes simplex virus virion host shutoff protein (vhs) is an mRNA-specific RNase that contributes to shutoff of host protein synthesis. We show here that vhs-induced mRNA decay proceeds 5′ to 3′ in an in vitro assay system derived from rabbit reticulocyte lysate.

Detalles Bibliográficos

Publicado en:	J Virol
Autores principales:	Perez-Parada, Jorge, Saffran, Holly A., Smiley, James R.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2004
Materias:	Virus-Cell Interactions
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC525032/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15542693/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.23.13391-13394.2004
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