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RNA Degradation Induced by the Herpes Simplex Virus vhs Protein Proceeds 5′ to 3′ In Vitro
The herpes simplex virus virion host shutoff protein (vhs) is an mRNA-specific RNase that contributes to shutoff of host protein synthesis. We show here that vhs-induced mRNA decay proceeds 5′ to 3′ in an in vitro assay system derived from rabbit reticulocyte lysate.
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC525032/ https://ncbi.nlm.nih.gov/pubmed/15542693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.23.13391-13394.2004 |
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