RNA Degradation Induced by the Herpes Simplex Virus vhs Protein Proceeds 5′ to 3′ In Vitro
The herpes simplex virus virion host shutoff protein (vhs) is an mRNA-specific RNase that contributes to shutoff of host protein synthesis. We show here that vhs-induced mRNA decay proceeds 5′ to 3′ in an in vitro assay system derived from rabbit reticulocyte lysate.
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| Udgivet i: | J Virol |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC525032/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15542693/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.23.13391-13394.2004 |
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