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RNA Degradation Induced by the Herpes Simplex Virus vhs Protein Proceeds 5′ to 3′ In Vitro

The herpes simplex virus virion host shutoff protein (vhs) is an mRNA-specific RNase that contributes to shutoff of host protein synthesis. We show here that vhs-induced mRNA decay proceeds 5′ to 3′ in an in vitro assay system derived from rabbit reticulocyte lysate.

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Perez-Parada, Jorge, Saffran, Holly A., Smiley, James R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2004
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC525032/
https://ncbi.nlm.nih.gov/pubmed/15542693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.23.13391-13394.2004
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