Integrity of Induced Pluripotent Stem Cell (iPSC) Derived Megakaryocytes as Assessed by Genetic and Transcriptomic Analysis

Previously, we have described our feeder-free, xeno-free approach to generate megakaryocytes (MKs) in culture from human induced pluripotent stem cells (iPSCs). Here, we focus specifically on the integrity of these MKs using: (1) genotype discordance between parent cell DNA to iPSC cell DNA and onwa...

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Publicat a:PLoS One
Autors principals: Kammers, Kai, Taub, Margaret A., Ruczinski, Ingo, Martin, Joshua, Yanek, Lisa R., Frazee, Alyssa, Gao, Yongxing, Hoyle, Dixie, Faraday, Nauder, Becker, Diane M., Cheng, Linzhao, Wang, Zack Z., Leek, Jeff T., Becker, Lewis C., Mathias, Rasika A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5249236/
https://ncbi.nlm.nih.gov/pubmed/28107356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167794
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