Transcriptional profile of platelets and iPSC-derived megakaryocytes from whole-genome and RNA sequencing

Genome-wide association studies have identified common variants associated with platelet-related phenotypes, but because these variants are largely intronic or intergenic, their link to platelet biology is unclear. In 290 normal subjects from the GeneSTAR Research Study (110 African Americans [AAs]...

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Dettagli Bibliografici
Pubblicato in:Blood
Autori principali: Kammers, Kai, Taub, Margaret A., Rodriguez, Benjamin, Yanek, Lisa R., Ruczinski, Ingo, Martin, Joshua, Kanchan, Kanika, Battle, Alexis, Cheng, Linzhao, Wang, Zack Z., Johnson, Andrew D., Leek, Jeffrey T., Faraday, Nauder, Becker, Lewis C., Mathias, Rasika A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2021
Soggetti:
Platelets and Thrombopoiesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7918180/
https://ncbi.nlm.nih.gov/pubmed/33094331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020006115
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