Integrity of Induced Pluripotent Stem Cell (iPSC) Derived Megakaryocytes as Assessed by Genetic and Transcriptomic Analysis

Previously, we have described our feeder-free, xeno-free approach to generate megakaryocytes (MKs) in culture from human induced pluripotent stem cells (iPSCs). Here, we focus specifically on the integrity of these MKs using: (1) genotype discordance between parent cell DNA to iPSC cell DNA and onwa...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Kammers, Kai, Taub, Margaret A., Ruczinski, Ingo, Martin, Joshua, Yanek, Lisa R., Frazee, Alyssa, Gao, Yongxing, Hoyle, Dixie, Faraday, Nauder, Becker, Diane M., Cheng, Linzhao, Wang, Zack Z., Leek, Jeff T., Becker, Lewis C., Mathias, Rasika A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2017
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5249236/
https://ncbi.nlm.nih.gov/pubmed/28107356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167794
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