Integrity of Induced Pluripotent Stem Cell (iPSC) Derived Megakaryocytes as Assessed by Genetic and Transcriptomic Analysis

Previously, we have described our feeder-free, xeno-free approach to generate megakaryocytes (MKs) in culture from human induced pluripotent stem cells (iPSCs). Here, we focus specifically on the integrity of these MKs using: (1) genotype discordance between parent cell DNA to iPSC cell DNA and onwa...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kammers, Kai, Taub, Margaret A., Ruczinski, Ingo, Martin, Joshua, Yanek, Lisa R., Frazee, Alyssa, Gao, Yongxing, Hoyle, Dixie, Faraday, Nauder, Becker, Diane M., Cheng, Linzhao, Wang, Zack Z., Leek, Jeff T., Becker, Lewis C., Mathias, Rasika A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5249236/
https://ncbi.nlm.nih.gov/pubmed/28107356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167794
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