Bioengineered iPSC-derived megakaryocytes for the detection of platelet-specific patient alloantibodies

Human platelet membrane glycoprotein polymorphisms can be immunogenic in man and are frequently the cause of clinically important immune reactions responsible for disorders such as neonatal alloimmune thrombocytopenia. Platelets from individuals carrying rare polymorphisms are often difficult to obt...

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Bibliographic Details
Published in:Blood
Main Authors: Zhang, Nanyan, Santoso, Sentot, Aster, Richard H., Curtis, Brian R., Newman, Peter J.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2019
Subjects:
Transfusion Medicine
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6887112/
https://ncbi.nlm.nih.gov/pubmed/31697836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019002225
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