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Bioengineered iPSC-derived megakaryocytes for the detection of platelet-specific patient alloantibodies

Human platelet membrane glycoprotein polymorphisms can be immunogenic in man and are frequently the cause of clinically important immune reactions responsible for disorders such as neonatal alloimmune thrombocytopenia. Platelets from individuals carrying rare polymorphisms are often difficult to obt...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Zhang, Nanyan, Santoso, Sentot, Aster, Richard H., Curtis, Brian R., Newman, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6887112/
https://ncbi.nlm.nih.gov/pubmed/31697836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019002225
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