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Serine Phosphorylation of SLP76 Is Dispensable for T Cell Development but Modulates Helper T Cell Function
The adapter protein SLP76 is a key orchestrator of T cell receptor (TCR) signal transduction. We previously identified a negative feedback loop that modulates T cell activation, involving phosphorylation of Ser376 of SLP76 by the hematopoietic progenitor kinase 1 (HPK1). However, the physiological r...
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| Udgivet i: | PLoS One |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5249077/ https://ncbi.nlm.nih.gov/pubmed/28107427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170396 |
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