Release of serine/threonine-phosphorylated adaptors from signaling microclusters down-regulates T cell activation

Antigen recognition within immunological synapses triggers and sustains T cell activation by nucleating protein microclusters that gather T cell receptors (TCRs), kinases, and adaptors. Dissipation of these microclusters results in signal termination, but how this process is regulated is unclear. In...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Lasserre, Rémi, Cuche, Céline, Blecher-Gonen, Ronnie, Libman, Evgeny, Biquand, Elise, Danckaert, Anne, Yablonski, Deborah, Alcover, Andrés, Di Bartolo, Vincenzo
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257567/
https://ncbi.nlm.nih.gov/pubmed/22105350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201103105
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados