Effect of lentivirus-mediated shRNA inactivation of HK1, HK2, and HK3 genes in colorectal cancer and melanoma cells

BACKGROUND: The switch from oxidative phosphorylation to glycolysis in proliferating cancer cells, even under aerobic conditions, has been shown first in 1926 by Otto Warburg. Today this phenomenon is known as the “Warburg effect” and recognized as a hallmark of cancer. The metabolic shift to glycol...

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書誌詳細
出版年:BMC Genet
主要な著者: Kudryavtseva, Anna V., Fedorova, Maria S., Zhavoronkov, Alex, Moskalev, Alexey A., Zasedatelev, Alexander S., Dmitriev, Alexey A., Sadritdinova, Asiya F., Karpova, Irina Y., Nyushko, Kirill M., Kalinin, Dmitry V., Volchenko, Nadezhda N., Melnikova, Nataliya V., Klimina, Kseniya M., Sidorov, Dmitry V., Popov, Anatoly Y., Nasedkina, Tatiana V., Kaprin, Andrey D., Alekseev, Boris Y., Krasnov, George S., Snezhkina, Anastasiya V.
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2016
主題:
Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5249010/
https://ncbi.nlm.nih.gov/pubmed/28105937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-016-0459-1
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