Effect of lentivirus-mediated shRNA inactivation of HK1, HK2, and HK3 genes in colorectal cancer and melanoma cells

BACKGROUND: The switch from oxidative phosphorylation to glycolysis in proliferating cancer cells, even under aerobic conditions, has been shown first in 1926 by Otto Warburg. Today this phenomenon is known as the “Warburg effect” and recognized as a hallmark of cancer. The metabolic shift to glycol...

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Publicado no:BMC Genet
Main Authors: Kudryavtseva, Anna V., Fedorova, Maria S., Zhavoronkov, Alex, Moskalev, Alexey A., Zasedatelev, Alexander S., Dmitriev, Alexey A., Sadritdinova, Asiya F., Karpova, Irina Y., Nyushko, Kirill M., Kalinin, Dmitry V., Volchenko, Nadezhda N., Melnikova, Nataliya V., Klimina, Kseniya M., Sidorov, Dmitry V., Popov, Anatoly Y., Nasedkina, Tatiana V., Kaprin, Andrey D., Alekseev, Boris Y., Krasnov, George S., Snezhkina, Anastasiya V.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5249010/
https://ncbi.nlm.nih.gov/pubmed/28105937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-016-0459-1
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