Effect of lentivirus-mediated shRNA inactivation of HK1, HK2, and HK3 genes in colorectal cancer and melanoma cells

BACKGROUND: The switch from oxidative phosphorylation to glycolysis in proliferating cancer cells, even under aerobic conditions, has been shown first in 1926 by Otto Warburg. Today this phenomenon is known as the “Warburg effect” and recognized as a hallmark of cancer. The metabolic shift to glycol...

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Bibliografiske detaljer
Udgivet i:BMC Genet
Main Authors: Kudryavtseva, Anna V., Fedorova, Maria S., Zhavoronkov, Alex, Moskalev, Alexey A., Zasedatelev, Alexander S., Dmitriev, Alexey A., Sadritdinova, Asiya F., Karpova, Irina Y., Nyushko, Kirill M., Kalinin, Dmitry V., Volchenko, Nadezhda N., Melnikova, Nataliya V., Klimina, Kseniya M., Sidorov, Dmitry V., Popov, Anatoly Y., Nasedkina, Tatiana V., Kaprin, Andrey D., Alekseev, Boris Y., Krasnov, George S., Snezhkina, Anastasiya V.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5249010/
https://ncbi.nlm.nih.gov/pubmed/28105937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-016-0459-1
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