Pancreatic β-Cells Express the Fetal Islet Hormone Gastrin in Rodent and Human Diabetes

β-Cell failure in type 2 diabetes (T2D) was recently proposed to involve dedifferentiation of β-cells and ectopic expression of other islet hormones, including somatostatin and glucagon. Here we show that gastrin, a stomach hormone typically expressed in the pancreas only during embryogenesis, is ex...

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Bibliografiske detaljer
Udgivet i:Diabetes
Main Authors: Dahan, Tehila, Ziv, Oren, Horwitz, Elad, Zemmour, Hai, Lavi, Judith, Swisa, Avital, Leibowitz, Gil, Ashcroft, Frances M., In’t Veld, Peter, Glaser, Benjamin, Dor, Yuval
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2017
Fag:
Islet Studies
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248995/
https://ncbi.nlm.nih.gov/pubmed/27864307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0641
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