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Pancreatic β-Cells Express the Fetal Islet Hormone Gastrin in Rodent and Human Diabetes
β-Cell failure in type 2 diabetes (T2D) was recently proposed to involve dedifferentiation of β-cells and ectopic expression of other islet hormones, including somatostatin and glucagon. Here we show that gastrin, a stomach hormone typically expressed in the pancreas only during embryogenesis, is ex...
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| Publicado no: | Diabetes |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Diabetes Association
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5248995/ https://ncbi.nlm.nih.gov/pubmed/27864307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0641 |
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