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Species-specific pharmacology of maximakinin, an amphibian homologue of bradykinin: putative prodrug activity at the human B(2) receptor and peptidase resistance in rats
Maximakinin (MK), an amphibian peptide possessing the C-terminal sequence of bradykinin (BK), is a BK B(2) receptor (B(2)R) agonist eliciting prolonged signaling. We reinvestigated this 19-mer for species-specific pharmacologic profile, in vivo confirmation of resistance to inactivation by angiotens...
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| Publicado no: | PeerJ |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
PeerJ Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5248581/ https://ncbi.nlm.nih.gov/pubmed/28133580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.2911 |
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