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D-Arg(0)-Bradykinin-Arg-Arg, a Latent Vasoactive Bradykinin B(2) Receptor Agonist Metabolically Activated by Carboxypeptidases

We previously reported hypotensive and vasodilator effects from C-terminally extended bradykinin (BK) sequences that behave as B(2) receptor (B(2)R) agonists activated by vascular or plasma peptidases. D-Arg(0)-BK-Arg-Arg (r-BK-RR) is a novel prodrug peptide hypothetically activated by two catalytic...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Bachelard, Hélène, Charest-Morin, Xavier, Marceau, François
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880945/
https://ncbi.nlm.nih.gov/pubmed/29636689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00273
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